Wednesday, December 5, 2007

Holidays bring the heart attack season

WASHINGTON - Those lords-a-leaping and ladies dancing may want to consider the downside of the holidays: Heart attack season has arrived. December and January are the deadliest months for heart disease, and many of the things that make the season merry are culprits: Rich meals, more alcohol — and all that extra stress.


But what may make the Christmas coronary more deadly than the same-size heart attack in, say, August, is a double dose of denial. It's not uncommon for people to initially shrug off chest pain as indigestion. Research suggests they're even more reluctant for a run to the emergency room when it means disrupting a holiday gathering, or if they've traveled to a strange city — meaning they arrive sicker.

Minutes matter.

"You have only a short window of opportunity to save heart muscle," warns Dr. William Suddath of Washington Hospital Center in the nation's capital — where a cardiac team on-duty 24 hours a day aims to start clearing victims' clogged arteries within 15 minutes of their arrival in the emergency room.

How bad each year is varies widely, but some hospitals say they saw an upswing in heart attacks start on Thanksgiving weekend. At Suddath's hospital, it started with a surprise spike the weekend before Thanksgiving — with so many critically ill patients that doctors ran out of a key heart-pumping machine and had to rent two extras.

Doctors have long braced for the seasonal upswing. A 2004 study confirmed it was a nationwide phenomenon, with peaks in death coinciding around the Christmas and New Year's holidays.

Why is harder to pin down. Vanderbilt University cardiologist Dr. Keith Churchwell says a "hurricane of factors" can tip someone at risk of a heart attack over the edge during this busy time of year.

"You can't be too busy to ignore your cardiovascular health," he says — but that's a key excuse he hears from his own patients.

Consider:

_Busy revelers tend to skip their medications, forget them when traveling or be unable to get refills far from home.

_What dieter can resist holiday goodies? The few extra pounds so many people gain will haunt you long-term. Right away, a particularly heavy meal, especially a high-fat one, stresses the heart as it is digested. Blood pressure and heart rate increase. There's even evidence that the lining of arteries becomes temporarily more clot-prone.

_Too much salt has an even more immediate effect, causing fluid retention that in turn makes the heart have to pump harder.

_Alcohol in moderation is considered heart-healthy. But if a round of holiday parties leaves you tipsy, that, too, makes your heart pump harder to get blood to peripheral arteries.

_Worse is something called "holiday heart syndrome," where alcohol literally irritates the heart muscle to trigger an irregular heartbeat called atrial fibrillation. If a-fib goes unchecked for too long, it in turn can cause a stroke.

_People say they're too busy to exercise, especially as it gets cold and darkness falls earlier. It can take months to build back up to pre-holiday exercise habits.

As for cold weather, it can constrict blood vessels, and the extra exertion of snow shoveling can cause a heart attack. The usual winter rise in respiratory diseases is another risk, adding further burden to a stressed heart — another reason to get a flu shot.

But the holiday spike happens even in warm climates.

And delay in treatment plays a role.

Hospitals may be short-staffed during the holidays, slowing the time it takes to diagnose a heart attack and start clearing the blocked artery, says Dr. Alice Jacobs of Boston University, past president of the American Heart Association.

The good news: The nation's hospitals are undergoing a major shift to speed care to heart attack sufferers. It's called "door to balloon time," and the aim is to reopen blocked arteries with angioplasties or other procedures within 90 minutes of arrival.

Only about a third of people suffering major heart attacks get such fast care now. But more than 900 hospitals have signed on to meet that challenge — sites that either are forming 24-hour cardiac catheterization teams like Suddath's, or making sure on-call doctors arrive within minutes, or ferrying patients to those angioplasty centers.

But for the hospital overhaul to work, patients can't hesitate when symptoms strike.

"If you have symptoms, don't ignore them, wherever you are," Jacobs stresses.

Yet realizing you're having a heart attack can be hard. Terry Bieber was just 50 when she woke up two days after Thanksgiving 2006 feeling what she thought was indigestion, got some Tums and returned to bed. Sometime later her husband realized she was sweating heavily while her skin was cold to the touch. Still, she argued when he went to call 911.

Like many women, Bieber didn't feel classic chest pain or pain radiating down her arm. She had to be helicoptered from the hospital near her Prince Frederick, Md., home to Washington Hospital Center for emergency angioplasty of two arteries.

"Don't take any chances," she now advises. "I had no clue at all that's what it was. ... If I had been by myself, I probably would not have called 911."

Sunday, December 2, 2007

Overnight shift to be classified as 'probable' cancer cause

LONDON, England (AP) -- Like UV rays and diesel exhaust fumes, working the graveyard shift will soon be listed as a "probable" cause of cancer.

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Graveyard shift work disrupts the circadian rhythm, the body's biological clock.

It is a surprising step validating a concept once considered wacky. And it is based on research that finds higher rates of breast and prostate cancer among women and men whose work day starts after dark.

Next month, the International Agency for Research on Cancer, the cancer arm of the World Health Organization, will add overnight shift work as a probable carcinogen.

The American Cancer Society says it will likely follow. Up to now, the U.S. organization has considered the work-cancer link to be "uncertain, controversial or unproven."

The higher cancer rates don't prove working overnight can cause cancer. There may be other factors common among graveyard shift workers that raise their risk for cancer.

However, scientists suspect that overnight work is dangerous because it disrupts the circadian rhythm, the body's biological clock. The hormone melatonin, which can suppress tumor development, is normally produced at night.

If the graveyard shift theory eventually proves correct, millions of people worldwide could be affected. Experts estimate that almost 20 percent of the working population in developed countries work night shifts.

Among the first to spot the night shift-cancer connection was Richard Stevens, a cancer epidemiologist and professor at the University of Connecticut Health Center. In 1987, Stevens published a paper suggesting a link between light at night and breast cancer.

Back then, he was trying to figure out why breast cancer incidence suddenly shot up starting in the 1930s in industrialized societies, where nighttime work was considered a hallmark of progress. Most scientists were bewildered by his proposal.

But in recent years, several studies have found that women working at night over many years were indeed more prone to breast cancer. Also, animals that have their light-dark schedules switched develop more cancerous tumors and die earlier.

Some research also suggests that men working at night may have a higher rate of prostate cancer.

Because these studies mostly focused on nurses and airline crews, bigger studies in different populations are needed to confirm or disprove the findings.

There are still plenty of skeptics. And to put the risk in perspective, the "probable carcinogen" tag means that the link between overnight work and cancer is merely plausible.

Among the long list of agents that are listed as "known" carcinogens are alcoholic beverages and birth control pills. Such lists say nothing about exposure amount or length of time or how likely they are to cause cancer. The American Cancer Society web site notes that carcinogens do not cause cancer at all times.

Still, many doubters of the night shift link may be won over by the IARC's analysis to be published in the December issue of the journal Lancet Oncology.

"The indications are positive," said Vincent Cogliano, who heads up the agency's carcinogen classifications unit. "There was enough of a pattern in people who do shift work to recognize that there's an increase in cancer, but we can't rule out the possibility of other factors."

Scientists believe having lower melatonin levels can raise the risk of developing cancer. Light shuts down melatonin production, so people working in artificial light at night may have lower melatonin levels.

Melatonin can be taken as a supplement, but experts don't recommend it long-term, since that could ruin the body's ability to produce it naturally.

Sleep deprivation may be another factor in cancer risk. People who work at night are not usually able to completely reverse their day and night cycles.

"Night shift people tend to be day shift people who are trying to stay awake at night," said Mark Rea, director of the Light Research Center at Rensselaer Polytechnic Institute in New York, who is not connected with the IARC analysis.

Not getting enough sleep makes your immune system vulnerable to attack, and less able to fight off potentially cancerous cells.

Confusing your body's natural rhythm can also lead to a breakdown of other essential tasks. "Timing is very important," Rea said. Certain processes like cell division and DNA repair happen at regular times.

Even worse than working an overnight shift is flipping between daytime and overnight work.

"The problem is resetting your body's clock," said Aaron Blair, of the United States' National Cancer Institute, who chaired IARC's recent meeting on shift work. "If you worked at night and stayed on it, that would be less disruptive than constantly changing shifts."

Anyone whose light and dark schedule is often disrupted -- including frequent long-haul travelers or insomniacs -- could theoretically face the same increased cancer risk, Stevens said.

He advises workers to sleep in a darkened room once they get off work. "The balance between light and dark is very important for your body. Just get a dark night's sleep."

Meanwhile, scientists are trying to come up with ways to reduce night workers' cancer risk. And some companies are experimenting with different lighting, seeking a type that doesn't affect melatonin production.

So far, the color that seems to have the least effect on melatonin is one that few people would enjoy working under: Red.

1980s Retro Makeup Application and Styles That Will Accentuate Any 80s Party Costume or Fashion Outfit.

Like all trends, '80s Makeup Trends seemed normal at the time, but looking back by twenty years or so, we can see the difference in the apparent natural look of today. In the eighties, women were coming into their own as far as workplace issues were concerned, and the trends were towards ultra-smooth color on the face, bright eye and lip shades and plenty of make up. The combination of workplace politics and cheap fluorescent lighting played absolute hell with women's makeup, turning foundations and eye shadows (blue was popular) into strange colors indeed. And makeup was important if you wanted to be taken seriously. It was quite usual for a woman to apply a full set of makeup—foundation, powder, lipstick and liner, mascara, eyeliner and eye shadow—to go to work. Like most fads, 80s makeup trends looked good: nowadays, women who make up that heavily look like they have something to hide.

For the perfect eighties theme party costume . . .

But if you're going to an 80's style retro party, you can easily create the eighties look. Fashions are easy: a matching dress or skirt suit with big shoulder pads, preferably in a bright color is a good start. Heels are imperative, and hair should be big and fluffy but very controlled. Remember, the '80s look is all about minimizing flaws but maximizing power. It was the decade of the woman's power suit, along with power lipsticks in bright reds and power perfumes heavy on the oriental floral scents. Need a model? For a perfect '80s hair style and suits, look at reruns of Designing Women.

Put some glamour into your eighties look

But if you're looking to do something more glam, Madonna is your model. Not the Madonna of today, with her London-Pilates-yoga chic, but the younger, earthy, in-your-face fashionista who successful combined wedding gowns with soldier boots. Any woman who was a teen in the eighties probably has a mental picture of Madonna that makes ordinary eighties clothing and makeup look like something from another century. Madonna wore makeup, all right, but she wasn't afraid to tear it up with plenty of white foundation and stark black eyeliners. Eighties fashion for the fashionable was all about extremes: shock had its value, and the idea that everyday women were wearing shoulder pads and big brass buttons to claim their share of the glass ceiling workplace was laughable. There was an interesting thing happening in the 1980's: some women were trying to climb the corporate ladder while others were trying to capitalize on a sort of brooding sexuality. The combination was confusing, since the clothes were hard edged but the faces were hidden under piles of makeup. It's almost like women had taken up full body and face armor to meet the wars of the workplace.

80s hair and make-up styles

Glam came along in the 1980s, and the cosmetic and clothing fashions were a combination of Star Trek and an Illinois Human Resources convention. Glam makeup practically preceded the wearer into the room: we're talking eyes so smoky they teared from all the goopy makeup, and big, pillowy, pouty lips, the kind of lips that say, "kiss me and then I'll sue you for sexual harassment". The average woman put on a lot of makeup, did things to her hair with curling irons and bright hair dye color, blow dryers and three kinds of gel, and then it was time to do her eyebrows.

More 80’s fashion and outfit ideas

Other 80's styles included workout gear, because the 80's was the time when aerobics really hit the big time. Jane Fonda's workout video made leg warmers a must-have, and it became fashionable to be thin so you could look really great in your gym wear. We saw the advent of lavender jogging suits for women, millions of cross trainers and meaningless little visors for running in the sun while it burned the top of your head. Sunglasses were big, so big in fact, that they reduced the wearer's face to the size of a bug's. Indoor glasses were also big and round, covering from cheek to eyebrow and resulting in glasses wearers pouring on even more eye makeup than ever before.